Vamorolone
Vamorolone (VBP15) is an orally bioavailable dissociative steroid that potently inhibits NF-κB, providing anti-inflammatory and membrane-stabilizing effects. It has demonstrated efficacy in improving outcomes in muscular dystrophy models while exhibiting a reduced side-effect profile compared to traditional corticosteroids in preclinical research.
Product Specifications
CAS Number
13209-41-1
Product Name Alternative
Dystrophy, Duchenne, muscular, inhibit, inflammation, Mineralocorticoid Receptor, NF-κB, NFκB, NF-kB, NFkB, Nuclear factor-κB, Nuclear factor-kappaB, membrane, Inhibitor, glucocorticoid, GlucocorticoidReceptor, Glucocorticoid Receptor, repair, Vamorolone, VBP 15, VBP15, VBP-15
Field of Research
Metabolism Research, Signal Transduction
Purity
98.04% (May vary between batches)
Solubility
DMSO:62.5 mg/mL (175.34 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.61 mM)
Smiles
[H][C@@]12C[C@@H] (C) [C@] (O) (C (=O) CO) [C@@]1 (C) CC=C1[C@@]2 ([H]) CCC2=CC (=O) C=C[C@]12C
Molecular Formula
C22H28O4
Molecular Weight
356.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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