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Vamorolone

Vamorolone (VBP15) is an orally bioavailable dissociative steroid that potently inhibits NF-κB, providing anti-inflammatory and membrane-stabilizing effects. It has demonstrated efficacy in improving outcomes in muscular dystrophy models while exhibiting a reduced side-effect profile compared to traditional corticosteroids in preclinical research.

Product Specifications

CAS Number

13209-41-1

Product Name Alternative

Dystrophy, Duchenne, muscular, inhibit, inflammation, Mineralocorticoid Receptor, NF-κB, NFκB, NF-kB, NFkB, Nuclear factor-κB, Nuclear factor-kappaB, membrane, Inhibitor, glucocorticoid, GlucocorticoidReceptor, Glucocorticoid Receptor, repair, Vamorolone, VBP 15, VBP15, VBP-15

Field of Research

Metabolism Research, Signal Transduction

Purity

98.04% (May vary between batches)

Solubility

DMSO:62.5 mg/mL (175.34 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.61 mM)

Smiles

[H][C@@]12C[C@@H] (C) [C@] (O) (C (=O) CO) [C@@]1 (C) CC=C1[C@@]2 ([H]) CCC2=CC (=O) C=C[C@]12C

Molecular Formula

C22H28O4

Molecular Weight

356.46

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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