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BRD7-IN-1

BRD7-IN-1 is a precursor to the PROTAC molecule VZ185, which potently degrades BRD7 and BRD9 with DC50 values in the low nanomolar range. This tool compound is used in chemical biology and oncology research to study bromodomain function and targeted protein degradation in cellular models.

Product Specifications

CAS Number

2448414-48-8

Product Name Alternative

BRD7, BRD7 IN 1, BRD7IN1, BRD-7-IN-1, BRD7, BRD9, BRD7-IN-1, BRD9, Epigenetic Reader Domain, EpigeneticReaderDomain, inhibit, Inhibitor

Field of Research

Epigenetics & Chromatin

Purity

98.95% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2.5 mg/mL (5.35 mM) ; H2O:100 mg/mL (213.95 mM) ; DMSO:30 mg/mL (64.19 mM)

Smiles

Cl.Cl.COc1cc (cc (OC) c1CN1CCNCC1) -c1cn (C) c (=O) c2cnccc12

Molecular Formula

C22H28Cl2N4O3

Molecular Weight

467.39

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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