Afatinib Dimaleate
Afatinib Dimaleate is an orally active, irreversible inhibitor of the ErbB (EGFR) family of receptor tyrosine kinases. This small molecule is used in research to study oncogenic signaling and has demonstrated antitumor activity in both cellular assays and animal models of non-small cell lung cancer and other solid tumors.
Product Specifications
CAS Number
850140-73-7
Product Name Alternative
Field of Research
Cardiovascular Research, Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Purity
98.11% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:252 mg/mL (350.94 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)
Smiles
OC (=O) \C=C/C (O) =O.OC (=O) \C=C/C (O) =O.CN (C) C\C=C\C (=O) Nc1cc2c (Nc3ccc (F) c (Cl) c3) ncnc2cc1O[C@H]1CCOC1
Molecular Formula
C32H33ClFN5O11
Molecular Weight
718.08
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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