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Methimazole

Methimazole (Thiamazole) is a hepatotoxic antithyroid agent used to induce and study hyperthyroidism in experimental models. It is widely applied in both in vitro and in vivo research to investigate thyroid hormone synthesis, drug-induced liver injury, and autoimmune thyroid disease mechanisms.

Product Specifications

CAS Number

60-56-0

Product Name Alternative

Cytotoxicity, antithyroid, hepatotoxicity, hepatocytes, Inhibitor, Methimazole, inhibit, Tapazole, THR, Thiamazole, Thyroid hormone receptor, Thyroidhormonereceptor (THR), Thyroidhormonereceptor, Thyroid peripheral conversion, Thyroid hormone receptor (THR)

Field of Research

Metabolism Research

Purity

99.21% (May vary between batches)

Solubility

H2O:21 mg/mL (183.94 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (17.52 mM) ; DMSO:60 mg/mL (525.53 mM) ; Ethanol:22 mg/mL (192.7 mM)

Smiles

CN1C=CN=C1S

Molecular Formula

C4H6N2S

Molecular Weight

114.17

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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