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L-Thyroxine

L-Thyroxine (NSC 36397), the primary thyroid hormone, is biosynthesized from iodinated tyrosine residues within thyroglobulin. It is a prohormone that is secreted and peripherally deiodinated to the active triiodothyronine (T3), making it essential for research into thyroid function, metabolic regulation, and endocrine signaling in both in vitro and in vivo models.

Product Specifications

CAS Number

51-48-9

Product Name Alternative

NSC 36397, NSC-36397, NSC36397, LThyroxine, L-Thyroxine, L Thyroxine, inhibit, Inhibitor, Levothyroxine, EndogenousMetabolite, Endogenous Metabolite, T 4, T-4, T4, Thyroid hormone, Thyroid hormone receptor, Thyroid Hormone Receptor, Thyroid hormone receptor (THR), Thyroidhormonereceptor (THR), Thyroidhormonereceptor, THR

Field of Research

Metabolism Research

Purity

97.63% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (4.25 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:93 mg/mL (119.71 mM)

Smiles

N[C@@H] (Cc1cc (I) c (Oc2cc (I) c (O) c (I) c2) c (I) c1) C (O) =O

Molecular Formula

C15H11I4NO4

Molecular Weight

776.87

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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