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IR415

IR415 is a potent small molecule inhibitor of Hepatitis B virus (HBx) with a 2 nM binding affinity. It blocks HBx-mediated suppression of RNAi by restoring dicer endoribonuclease activity, thereby inhibiting HBV replication. This mechanism supports its utility in both in vitro and in vivo virology and antiviral research.

Product Specifications

CAS Number

452967-14-5

Product Name Alternative

HBV, HBX, hepatitis B, Hepatitis B virus, Hepatitis B virus X protein (HBx), HepG2, Inhibitor, inhibit, IR415, IR-415, IR415-HBx interaction, IR 415, cell, replication, VSR, virus

Field of Research

Infectious Disease & Virology

Purity

99.05% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (13.5 mM) ; DMSO:125 mg/mL (421.81 mM)

Smiles

Fc1ccc (NC (=S) NCCCn2ccnc2) c (F) c1

Molecular Formula

C13H14F2N4S

Molecular Weight

296.34

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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