KPLH1130
KPLH1130 is a selective pyruvate dehydrogenase kinase (PDK) inhibitor that improves glucose tolerance in high-fat diet-fed mice. Its mechanism involves suppressing macrophage polarization and pro-inflammatory responses, making it a useful research tool for studying metabolic inflammation in both in vivo and in vitro models.
Product Specifications
CAS Number
906669-07-6
Product Name Alternative
Inhibitor, inhibit, KPLH 1130, KPLH1130, KPLH-1130, PDHK, PDH, PDH kinase, PDK, Pyruvate dehydrogenase kinase
Field of Research
Metabolism Research, Signal Transduction
Purity
98.43% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (14.12 mM) ; DMSO:83.33 mg/mL (294.16 mM)
Smiles
Cc1ccc (cc1) -n1c (n[nH]c1=O) -c1ccc (O) cc1O
Molecular Formula
C15H13N3O3
Molecular Weight
283.28
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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