Erlotinib HCl
Erlotinib hydrochloride is a potent and selective EGFR tyrosine kinase inhibitor (IC50 = 2 nM) . It is widely used in cancer research, particularly for studying non-small cell lung cancer, and has been validated in both in vitro cell-based assays and in vivo animal models.
Product Specifications
CAS Number
183319-69-9
Product Name Alternative
ErbB-1, Erlotinib, Erlotinib HCl, Erlotinib hydrochloride, Erlotinib Hydrochloride, EGFR, Epidermal growth factor receptor, HER1, NSC 718781, NSC718781, NSC-718781, Inhibitor, inhibit, CP358774, CP-358774, CP 358774, Autophagy, OSI744, OSI-744, OSI774, OSI-774, OSI 744, OSI 774
Field of Research
Cardiovascular Research, Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Purity
>98%
Bioactivity
EGFR Kinase inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 18 mg/ml with warming) .
Smiles
Cl.COCCOC1=C (OCCOC) C=C2C (NC3=CC (=CC=C3) C#C) =NC=NC2=C1
Molecular Formula
C22H23N3O4 · HCl
Molecular Weight
429.91
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
N- (3-Ethynylphenyl) -6,7-bis (2-methoxyethoxy) quinazolin-4-amine hydrochloride
Available Sizes
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