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Promethazine hydrochloride

Promethazine HCl is a first-generation antihistamine and potent H1 receptor antagonist, with moderate activity at mACh, 5-HT2A/2C, D2, and α1-adrenergic receptors. It is widely used in research for studying allergic responses, neurotransmitter pathways, and sedation mechanisms in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

58-33-3

Product Name Alternative

Inhibitor, HistamineReceptor, Histamine Receptor, H1 receptor, inhibit, AdrenergicReceptor, Adrenergic Receptor, α-adrenergic receptor, Phenergan, Promethazine, Promethazine HCl, Promethazine hydrochloride, Promethazine Hydrochloride

Field of Research

Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery

Purity

95.36% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.23 mM) ; DMSO:55 mg/mL (171.4 mM)

Smiles

Cl.CC (CN1c2ccccc2Sc2ccccc12) N (C) C

Molecular Formula

C17H20N2S·HCl

Molecular Weight

320.88

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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