Clozapine
Clozapine is an atypical antipsychotic with a unique multi-receptor profile, acting as a potent serotonin 5-HT2A/2C antagonist with only weak D2 dopamine receptor blockade. It is widely used in research to study treatment-resistant schizophrenia mechanisms and receptor interactions in both in vitro binding assays and in vivo animal models.
Product Specifications
CAS Number
5786-21-0
Product Name Alternative
Clozapine, Beta Receptor, Dopamine Receptor, DopamineReceptor, D2, antipsychotic, 5-hydroxytryptamine Receptor, Adrenergic Receptor, AdrenergicReceptor, 5-HT Receptor, HeLa, HF1854, HF-1854, HF 1854, Inhibitor, inhibit, Muscarinic acetylcholine receptor, mAChR, M1 mAChR, LX 100-129, α2-adrenoceptor, schizophrenia, psychosis, Serotonin Receptor
Field of Research
Neuroscience
Purity
>98%
Bioactivity
Dopamine D2/D4 antagonist
Form
Powder
Solubility
Soluble in DMSO (up to 30 mg/ml) .
Smiles
CN1CCN (CC1) C1=NC2=C (NC3=C1C=CC=C3) C=CC (Cl) =C2
Molecular Formula
C18H19ClN4
Molecular Weight
326.82
Storage Conditions
RT
Notes
For research use only.
Other Product Names
8-Chloro-11- (4-methyl-1-piperazinyl) -5/H-dibenzo[b, e]diazepine
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