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Clozapine

Clozapine is an atypical antipsychotic with a unique multi-receptor profile, acting as a potent serotonin 5-HT2A/2C antagonist with only weak D2 dopamine receptor blockade. It is widely used in research to study treatment-resistant schizophrenia mechanisms and receptor interactions in both in vitro binding assays and in vivo animal models.

Product Specifications

CAS Number

5786-21-0

Product Name Alternative

Clozapine, Beta Receptor, Dopamine Receptor, DopamineReceptor, D2, antipsychotic, 5-hydroxytryptamine Receptor, Adrenergic Receptor, AdrenergicReceptor, 5-HT Receptor, HeLa, HF1854, HF-1854, HF 1854, Inhibitor, inhibit, Muscarinic acetylcholine receptor, mAChR, M1 mAChR, LX 100-129, α2-adrenoceptor, schizophrenia, psychosis, Serotonin Receptor

Field of Research

Neuroscience

Purity

>98%

Bioactivity

Dopamine D2/D4 antagonist

Form

Powder

Solubility

Soluble in DMSO (up to 30 mg/ml) .

Smiles

CN1CCN (CC1) C1=NC2=C (NC3=C1C=CC=C3) C=CC (Cl) =C2

Molecular Formula

C18H19ClN4

Molecular Weight

326.82

Storage Conditions

RT

Notes

For research use only.

Other Product Names

8-Chloro-11- (4-methyl-1-piperazinyl) -5/H-dibenzo[b, e]diazepine

Available Sizes

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