Dimethyl fumarate
Dimethyl fumarate (DMF) is an orally active, blood-brain barrier permeable Nrf2 activator. It exhibits antimicrobial, anti-inflammatory, and immunomodulatory properties, making it a valuable research tool for studying multiple sclerosis and neuroinflammatory diseases in both in vitro and in vivo models.
Product Specifications
CAS Number
624-49-7
Product Name Alternative
EndogenousMetabolite, Endogenous Metabolite, Inhibitor, Human immunodeficiency virus, HIVProtease, HIV Protease, HIV, neuroprotective, KEAP1-Nrf2, Keap1-Nrf2, inhibit, Autophagy, Antioxidant, anti-inflammatory, brain-penetrant, DMF, Dimethyl, Dimethyl fumarate, Dimethyl Fumarate, ROS, sclerosis, ReactiveOxygenSpecies, Reactive Oxygen Species
Field of Research
Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research, Pharmacology & Drug Discovery, Protein Biochemistry, Signal Transduction
Purity
90.51% (May vary between batches)
Solubility
10% DMSO+90% Saline:1.5 mg/mL (10.41 mM) ; DMSO:40 mg/mL (277.53 mM) ; Ethanol:7.2 mg/mL (49.95 mM) ;5% DMSO+95% Saline:0.29 mg/mL (2.01 mM)
Smiles
C (/C=C/C (OC) =O) (OC) =O
Molecular Formula
C6H8O4
Molecular Weight
144.13
Storage Conditions
-20°C
Notes
For research use only.
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