CDK4/6-IN-2
CDK4/6-IN-2 is a highly potent and selective dual inhibitor of cyclin-dependent kinases 4 and 6, with IC50 values of 2.7 nM and 16 nM, respectively. It is a valuable chemical probe for studying cell cycle progression in cancer research, applicable in both in vitro biochemical assays and cellular proliferation studies.
Product Specifications
CAS Number
1800506-48-2
Product Name Alternative
CDK4, CDK, CDK6, CDK4/6-IN-2, CDK4/6IN2, CDK-4/6-IN-2, CDK4/6 IN 2, Cyclin dependent kinase, inhibit, Inhibitor
Field of Research
Cell Biology, Signal Transduction
Purity
99.47% (May vary between batches)
Solubility
DMSO:< 1 mg/mL (insoluble or slightly soluble)
Smiles
CCN1CCN (Cc2cnc (Nc3cc (c (F) cn3) -c3cc (F) c4nc (C) n (C (C) C) c4c3) nc2) CC1
Molecular Formula
C27H32F2N8
Molecular Weight
506.59
Storage Conditions
-20°C
Notes
For research use only.
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