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CDK4/6-IN-2

CDK4/6-IN-2 is a highly potent and selective dual inhibitor of cyclin-dependent kinases 4 and 6, with IC50 values of 2.7 nM and 16 nM, respectively. It is a valuable chemical probe for studying cell cycle progression in cancer research, applicable in both in vitro biochemical assays and cellular proliferation studies.

Product Specifications

CAS Number

1800506-48-2

Product Name Alternative

CDK4, CDK, CDK6, CDK4/6-IN-2, CDK4/6IN2, CDK-4/6-IN-2, CDK4/6 IN 2, Cyclin dependent kinase, inhibit, Inhibitor

Field of Research

Cell Biology, Signal Transduction

Purity

99.47% (May vary between batches)

Solubility

DMSO:< 1 mg/mL (insoluble or slightly soluble)

Smiles

CCN1CCN (Cc2cnc (Nc3cc (c (F) cn3) -c3cc (F) c4nc (C) n (C (C) C) c4c3) nc2) CC1

Molecular Formula

C27H32F2N8

Molecular Weight

506.59

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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