Theophylline
Theophylline (1,3-Dimethylxanthine) is a natural methylxanthine found in tea that acts as a non-selective phosphodiesterase inhibitor, elevating intracellular cAMP levels. This mechanism underpins its research applications in studying bronchial relaxation, cardiac stimulation, and inflammatory pathways in both cellular and animal models.
Product Specifications
CAS Number
58-55-9
Product Name Alternative
Chronic obstructive pulmonary disease, Endogenous Metabolite, Autophagy, asthma, 1,3-Dimethylxanthine, airway smooth muscle, Adenosine Receptor, Adenosine receptor, AdenosineReceptor, A549 cells, HDAC2, Inhibitor, EndogenousMetabolite, eosinophils, PDE, NF-κB, inhibit, I-κBα, P1 receptor, Theophylline, Theo 24, Theo24, Theo-24, Phosphodiesterase (PDE), phosphodiesterase
Field of Research
Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Metabolism Research, Molecular Biology, Neuroscience, Pharmacology & Drug Discovery
Purity
99.47% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (5.55 mM) ; DMSO:16.83 mg/mL (93.42 mM)
Smiles
CN1C2=C (NC=N2) C (=O) N (C) C1=O
Molecular Formula
C7H8N4O2
Molecular Weight
180.16
Storage Conditions
-20°C
Notes
For research use only.
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