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Deschloroclozapine

Deschloroclozapine, a Clozapine metabolite, is a potent and selective agonist for chemogenetic DREADDs (hM3Dq & hM4Di), with binding affinities (Ki) of 6.3 and 4.2 nM respectively. It is a key research tool for precise neuronal modulation in vivo and in vitro for neuroscience and behavioral studies.

Product Specifications

CAS Number

1977-07-7

Product Name Alternative

Dopamne D1, Dopamne D2, Dopamne D4, DREADDs, Deschloroclozapine, Muscarinic acetylcholine receptor, muscarinic-based, inhibit, Inhibitor, mAChR, hM3Dq, hM4Di, Serotonin S2A, Serotonin S2C, Serotonin S3, Serotonin Transporter, SerotoninTransporter, serotonin

Field of Research

Neuroscience

Purity

99.61% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (13.68 mM) ; DMSO:127.5 mg/mL (436.08 mM)

Smiles

CN1CCN (CC1) C1=Nc2ccccc2Nc2ccccc12

Molecular Formula

C18H20N4

Molecular Weight

292.38

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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