Deschloroclozapine
Deschloroclozapine, a Clozapine metabolite, is a potent and selective agonist for chemogenetic DREADDs (hM3Dq & hM4Di), with binding affinities (Ki) of 6.3 and 4.2 nM respectively. It is a key research tool for precise neuronal modulation in vivo and in vitro for neuroscience and behavioral studies.
Product Specifications
CAS Number
1977-07-7
Product Name Alternative
Dopamne D1, Dopamne D2, Dopamne D4, DREADDs, Deschloroclozapine, Muscarinic acetylcholine receptor, muscarinic-based, inhibit, Inhibitor, mAChR, hM3Dq, hM4Di, Serotonin S2A, Serotonin S2C, Serotonin S3, Serotonin Transporter, SerotoninTransporter, serotonin
Field of Research
Neuroscience
Purity
99.61% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (13.68 mM) ; DMSO:127.5 mg/mL (436.08 mM)
Smiles
CN1CCN (CC1) C1=Nc2ccccc2Nc2ccccc12
Molecular Formula
C18H20N4
Molecular Weight
292.38
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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