Rineterkib
ERK-IN-1 (Rineterkib) is a selective small molecule inhibitor targeting RAF and ERK1/2 kinases within the MAPK signaling cascade. It is utilized in preclinical research to investigate oncogenic pathways and has demonstrated activity in both cellular assays and in vivo models of cancer.
Product Specifications
CAS Number
1715025-32-3
Product Name Alternative
KRAS, inhibit, NSCLC, MAPK, Inhibitor, G12C, G12D, G12V, ERK, ERK1, ERK2, ERK-IN-1, Extracellular signal regulated kinases, Rineterkib, Raf kinases, RAF, Raf
Field of Research
Signal Transduction
Purity
98.40% (May vary between batches)
Solubility
DMSO:60 mg/mL (103.73 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (8.64 mM)
Smiles
CNC[C@@H] (NC (=O) c1ccc (cc1F) -c1nc (cnc1N) [C@H]1CC[C@H] (O) [C@@H] (F) C1) c1cc (F) cc (Br) c1
Molecular Formula
C26H27BrF3N5O2
Molecular Weight
578.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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