FLT3-IN-3
FLT3-IN-3 is a potent small molecule inhibitor targeting both wild-type FLT3 and the D835Y mutant, with IC50 values of 13 nM and 8 nM, respectively. It is a valuable research tool for investigating FLT3-driven pathologies, such as acute myeloid leukemia, in both cellular and animal model studies.
Product Specifications
CAS Number
2229050-90-0
Product Name Alternative
Inhibit, Inhibitor, FLT3, FLT3 (D835Y), FLT3 (WT), FLT3 D835Y, FLT3 IN 3, FLT3 WT, FLT3IN3, FLT-3-IN-3, FLT3-IN-3, Fms like tyrosine kinase 3, CD135, Cluster of differentiation antigen 135
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Purity
99.25% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (10.19 mM) ; DMSO:250 mg/mL (509.54 mM)
Smiles
N[C@H]1CC[C@@H] (CC1) Nc1nc (Nc2ccc (CN3CCOCC3) cc2) c2ncn (C3CCCC3) c2n1
Molecular Formula
C27H38N8O
Molecular Weight
490.64
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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