Lys-SMCC-DM1

Lys-SMCC-DM1 is an antibody-drug conjugate (ADC) designed to target HER2, delivering the potent microtubule-disrupting agent DM1. It is widely utilized in breast cancer research for investigating ADC mechanisms and efficacy in both cellular (in vitro) and animal (in vivo) experimental models.

Product Specifications

CAS Number

1281816-04-3

Product Name Alternative

Lys-Nε-MCC-DM1, LysSMCCDM1, Lys-SMCC-DM1, Lys-SMCC-DM-1, Lys SMCC DM1, Microtubule Associated, MicrotubuleAssociated, linker-payload, inhibit, Maytansinoids, HER2, Inhibitor, growth inhibitory, Drug-Linker Conjugates for ADC, DrugLinker Conjugates for ADC, DrugLinkerConjugatesforADC, tubulin polymerization, tubulin

Field of Research

Signal Transduction

Purity

≥98% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (1.81 mM) ; DMSO:60 mg/mL (54.36 mM)

Smiles

C[C@]12[C@@] (O1) ([C@H] (C) [C@@]3 (C[C@] (O) ([C@H] (OC) /C=C/C=C (\C) /CC4=CC (N (C) C (=O) C[C@@H]2OC ([C@@H] (N (C (CCS[C@@H]5C (=O) N (C[C@@H]6CC[C@@H] (C (NCCCC[C@@H] (C (O) =O) N) =O) CC6) C (=O) C5) =O) C) C) =O) =C (Cl) C (OC) =C4) NC (=O) O3) [H]) [H]