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Navitoclax-piperazine

Navitoclax-piperazine, also known as ABT-263-piperazine, is a potent and selective BCL-XL inhibitor. It is widely used in oncology research, demonstrating efficacy in inducing apoptosis in cellular assays and showing activity in preclinical in vivo models of hematologic cancers.

Product Specifications

CAS Number

2143096-93-7

Product Name Alternative

ABT-263-piperazine, B-cell, Bcl-xL, Bcl-2 Family, Ligands for Target Protein for PROTAC, LigandsforTargetProteinforPROTAC, ligase, inhibit, lymphoma, Navitoclax piperazine, Navitoclaxpiperazine, Navitoclax-piperazine, Inhibitor, Target Protein-binding Moiety, VHL, ubiquitin

Field of Research

Cell Biology, Pharmacology & Drug Discovery

Purity

99.11% (May vary between batches)

Solubility

10% DMSO+90% Corn Oil:3.3 mg/mL (3.39 mM) ; DMSO:250 mg/mL (256.77 mM)

Smiles

CC1 (C) CCC (=C (CN2CCN (CC2) c2ccc (cc2) C (=O) NS (=O) (=O) c2ccc (N[C@H] (CCN3CCNCC3) CSc3ccccc3) c (c2) S (=O) (=O) C (F) (F) F) C1) c1ccc (Cl) cc1

Molecular Formula

C47H56ClF3N6O5S3

Molecular Weight

973.63

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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