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NF-56-EJ40

NF-56-EJ40 is a potent and selective human SUCNR1 (GPR91) antagonist, exhibiting an IC50 of 25 nM and a Ki of 33 nM. This tool compound is valuable for investigating the role of succinate signaling in metabolic disorders, inflammation, and hypertension in both cellular and animal models.

Product Specifications

CAS Number

2380230-73-7

Product Name Alternative

GPR91, Inhibitor, inhibit, NF56EJ40, NF-56-EJ40, NF-56-EJ-40, NF 56 EJ40, SUCNR1, SUCNR1 (GPR91)

Field of Research

Pharmacology & Drug Discovery

Purity

99.51% (May vary between batches)

Solubility

H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:2 mg/mL (4.51 mM)

Smiles

CN1CCN (Cc2ccc (cc2) -c2cccc (c2) C (=O) Nc2ccccc2CC (O) =O) CC1

Molecular Formula

C27H29N3O3

Molecular Weight

443.54

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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