NF-56-EJ40
NF-56-EJ40 is a potent and selective human SUCNR1 (GPR91) antagonist, exhibiting an IC50 of 25 nM and a Ki of 33 nM. This tool compound is valuable for investigating the role of succinate signaling in metabolic disorders, inflammation, and hypertension in both cellular and animal models.
Product Specifications
CAS Number
2380230-73-7
Product Name Alternative
GPR91, Inhibitor, inhibit, NF56EJ40, NF-56-EJ40, NF-56-EJ-40, NF 56 EJ40, SUCNR1, SUCNR1 (GPR91)
Field of Research
Pharmacology & Drug Discovery
Purity
99.51% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:2 mg/mL (4.51 mM)
Smiles
CN1CCN (Cc2ccc (cc2) -c2cccc (c2) C (=O) Nc2ccccc2CC (O) =O) CC1
Molecular Formula
C27H29N3O3
Molecular Weight
443.54
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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