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Doxapram hydrochloride hydrate

Doxapram hydrochloride hydrate is a potent inhibitor of TASK channel subtypes, with EC50 values of 410 nM for TASK-1, 9 μM for TASK-1/TASK-3 heterodimers, and 37 μM for TASK-3. This small molecule is a valuable research tool for studying the role of TASK channels in respiratory control, neuronal excitability, and cellular physiology in both in vitro and in vivo models.

Product Specifications

CAS Number

7081-53-0

Product Name Alternative

Doxapram HCl, Doxapram hydrochloride, Doxapram Hydrochloride, Doxapram hydrochloride hydrate, Doxapram hydrochloride Hydrate, Doxapram hydrochloride monohydrate, Doxapram hydrochloride Monohydrate, Inhibitor, KcsA, inhibit, PotassiumChannel, Potassium Channel, TASK-1, TASK-1/TASK-3 heterodimeric, TASK-3

Field of Research

Pharmacology & Drug Discovery

Purity

99.64% (May vary between batches)

Solubility

Ethanol:2 mg/mL (4.62 mM) ; H2O:23 mg/mL (53.12 mM) ; DMSO:81 mg/mL (187.07 mM)

Smiles

Cl.CCN1CC (CCN2CCOCC2) C (C1=O) (c1ccccc1) c1ccccc1

Molecular Formula

C24H33ClN2O3 (C24H30N2O2·ClH·H2O)

Molecular Weight

432.99

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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