Lapatinib ditosylate monohydrate
Lapatinib ditosylate monohydrate is a tyrosine kinase inhibitor used to treat advanced breast cancer and other solid tumors. It is widely employed in both in vitro and in vivo cancer research to study EGFR and HER2 signaling pathways. Its use is associated with transient aminotransferase elevations and rare cases of acute liver injury.
Product Specifications
CAS Number
388082-78-8
Product Name Alternative
Lapatinib ditoluenesulfonate, Lapatinib ditoluenesulfonate monohydrate, Lapatinib ditosilate hydrate, Lapatinib ditosylate monohydrate, HER2/ErbB2, EGFR, Ferroptosis, GW2016 ditosylate, GW572016 ditosylate, Autophagy, Tyverb, Tyverb ditosylate monohydrate, Tykerb, Tykerb ditosylate monohydrate
Field of Research
Cardiovascular Research, Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Purity
98.00% (May vary between batches)
Solubility
DMSO:91 mg/mL (96.45 mM)
Smiles
N1cnc (c2cc (ccc12) c1oc (cc1) CNCCS (=O) (=O) C) Nc1cc (c (cc1) OCc1cc (ccc1) F) Cl.c1 (ccc (cc1) C) S (=O) (=O) O.O.c1 (ccc (cc1) C) S (=O) (=O) O
Molecular Formula
C29H26ClFN4O4S·2 (C7H8O3S) ·H2O
Molecular Weight
943.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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