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Quetiapine

Quetiapine (ICI204636) is an atypical antipsychotic used in schizophrenia and bipolar I disorder research. Its mechanism involves antagonism of dopamine (D1, D2), serotonin (5-HT1A, 5-HT2), adrenergic (α1, α2), and histamine H1 receptors, making it a valuable tool for in vitro and in vivo neuropharmacology studies.

Product Specifications

CAS Number

111974-69-7

Product Name Alternative

DopamineReceptor, Dopamine Receptor, Dopamine, Antidepressant, anxiolytic, 5-HT2C, 5-HT Receptor, 5HT Receptor, 5-HT1A, 5-HT2A, Adrenergic Receptor, AdrenergicReceptor, 5-hydroxytryptamine Receptor, 5HTReceptor, 5-HT, H1 receptor, ICI204636, ICI-204636, ICI 204636, Inhibitor, Histamine Receptor, HistamineReceptor, inhibit, mAChR, Serotonin Receptor, Quetiapin, Quetiapine

Field of Research

Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery

Purity

99.14% (May vary between batches)

Solubility

H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.21 mM) ; DMSO:120 mg/mL (312.9 mM)

Smiles

OCCOCCN1CCN (CC1) C1=Nc2ccccc2Sc2ccccc12

Molecular Formula

C21H25N3O2S

Molecular Weight

383.51

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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