Docetaxel trihydrate
Docetaxel trihydrate is a microtubule-stabilizing antineoplastic agent central to treating solid tumors like breast and lung cancer. It is widely used in both in vitro cytotoxicity assays and in vivo xenograft models to study mechanisms of mitotic inhibition and drug resistance. While generally well-tolerated, it can induce hepatic injury, typically in severe hypersensitivity reactions.
Product Specifications
CAS Number
148408-66-6
Product Name Alternative
Docetaxel, Docetaxel trihydrate, Docetaxel Trihydrate, Apoptosis, Bcl-2, inhibit, Microtubule/Tubulin, MicrotubuleAssociated, Microtubule Associated, Inhibitor, Tubulin β-1 chain, RP 56976, RP56976, RP-56976, RP56976 (NSC 628503), RP56976 (NSC 628503) Trihydrate, RP-56976 (Trihydrate)
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Purity
98.68% (May vary between batches)
Solubility
Ethanol:100 mg/mL (116.02 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (4.64 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:100 mg/mL (116.02 mM)
Smiles
O.O.O.CC (=O) O[C@@]12CO[C@@H]1C[C@H] (O) [C@]1 (C) [C@@H]2[C@H] (OC (=O) c2ccccc2) [C@]2 (O) C[C@H] (OC (=O) C (O) C (NC (=O) OC (C) (C) C) c3ccccc3) C (C) =C ([C@@H] (O) C1=O) C2 (C) C
Molecular Formula
C43H59NO17
Molecular Weight
861.95
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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