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Gemcitabine

Gemcitabine (LY188011) is a synthetic nucleoside analog that inhibits DNA synthesis, exhibiting antitumor activity by inducing both autophagy and apoptosis. It is widely used in cancer research, including in vitro cell studies and in vivo models for pancreatic, lung, and breast carcinomas.

Product Specifications

CAS Number

95058-81-4

Product Name Alternative

RNA Synthesis, RNASynthesis, Inhibitor, Gemcitabine, inhibit, NSC 613327, NSC613327, NSC-613327, LY188011, LY-188011, LY 188011, Nucleoside Antimetabolite/Analog, NucleosideAntimetabolite, Nucleoside Antimetabolite, Apoptosis, Analog, Autophagy, DNA/RNA Synthesis, DNA synthesis, DNA Synthesis, DNASynthesis

Field of Research

Cell Biology, Molecular Biology, Pharmacology & Drug Discovery

Purity

98.66% (May vary between batches)

Solubility

DMSO:125 mg/mL (474.92 mM) ; Ethanol:12.5 mg/mL (47.49 mM) ; H2O:6.25 mg/mL (23.75 mM) ;5% DMSO+95% Saline:0.75 mg/mL (2.85 mM)

Smiles

NC1=NC (=O) N (C=C1) [C@@H]1O[C@H] (CO) [C@@H] (O) C1 (F) F

Molecular Formula

C9H11F2N3O4

Molecular Weight

263.20

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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