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Pravastatin sodium

Pravastatin sodium is a potent HMG-CoA reductase inhibitor, demonstrating an IC50 of 5.6 μM for sterol synthesis inhibition. It is widely used in research to study cholesterol metabolism and atherosclerosis, with applications in both in vitro enzymatic assays and in vivo animal models of hyperlipidemia.

Product Specifications

CAS Number

81131-70-6

Product Name Alternative

Pravastatin sodium, Pravastatin, Inhibitor, HMG-CoA Reductase (HMGCR), HMGCoAReductase, HMG-CoA reductase, HMGCoA Reductase, HMGCR, Ferroptosis, inhibit, CS 514, CS514, CS-514, CS-514 (sodium), CS-514 Sodium, Autophagy

Field of Research

Cell Biology, Metabolism Research, Pharmacology & Drug Discovery

Purity

97.14% (May vary between batches)

Solubility

DMSO:247.5 mg/mL (554.29 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.48 mM) ; H2O:44.7 mg/mL (100.11 mM)

Smiles

[C@H]12[C@H] (C[C@H] (O) C=C1C=C[C@H] (C) [C@@H]2CC[C@@H] (O) C[C@@H] (O) CC (=O) [O-]) OC (=O) [C@@H] (C) CC.[Na+]

Molecular Formula

C23H35NaO7

Molecular Weight

446.52

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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