RBN-2397
RBN-2397 is a highly potent and selective, orally bioavailable PARP7 inhibitor that competes with NAD+ across multiple species, exhibiting an IC50 below 3 nM. It is a valuable research tool for studying PARP7's role in cancer biology and has demonstrated antitumor activity in both cellular assays and in vivo models.
Product Specifications
CAS Number
2381037-82-5
Product Name Alternative
Cell, carcinoma, advanced, ovarian, NSCLC, metastatic, PARP, PARP7, PARP-7, lung, Inhibitor, inhibit, squamous, solid, RBN 2397, RBN2397, RBN-2397, poly ADP ribose polymerase, tumor
Field of Research
Epigenetics & Chromatin, Molecular Biology
Purity
98.48% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (9.55 mM) ; DMSO:247 mg/mL (471.89 mM)
Smiles
C[C@@H] (COCCC (=O) N1CCN (CC1) c1ncc (cn1) C (F) (F) F) Nc1cn[nH]c (=O) c1C (F) (F) F
Molecular Formula
C20H23F6N7O3
Molecular Weight
523.43
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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