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Tipepidine hydrochloride

Tipepidine hydrochloride is a reversible dopamine D2 receptor antagonist that inhibits associated GIRK channel currents (IC50 = 7.0 μM) . This compound exhibits antidepressant-like effects in animal models and serves as a useful research tool for studying dopaminergic signaling and mood-related disorders in both in vitro and in vivo experimental systems.

Product Specifications

CAS Number

1449686-84-3

Product Name Alternative

Tipepidine, Tipepidine hydrochloride, Tipepidine Hydrochloride, PotassiumChannel, Potassium Channel, KcsA, inhibit, Inhibitor, dopamine D2 receptor, Dopamine Receptor, DopamineReceptor, D2

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Purity

99.97% (May vary between batches)

Solubility

DMSO:41.67 mg/mL (133.6 mM) ; H2O:50 mg/mL (160.31 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.41 mM)

Smiles

Cl.CN1CCCC (C1) =C (c1cccs1) c1cccs1

Molecular Formula

C15H18ClNS2

Molecular Weight

311.89

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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