Ergolide
Ergolide, a sesquiterpene lactone from Inula britannica, suppresses iNOS and COX-2 expression in RAW 264.7 macrophages via NF-κB inhibition. This activity supports its research use in studying inflammation pathways, with applications in both in vitro and in vivo models of inflammatory diseases.
Product Specifications
CAS Number
54999-07-4
Product Name Alternative
Ergolide, Inhibitor, inhibit, NF-κB, NFkB, NF-kB, NFκB, Nuclear factor-kappaB, Nuclear factor-κB
Field of Research
Signal Transduction
Purity
99.56% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:2.5 mg/mL (8.16 mM) ; DMSO:50 mg/mL (163.21 mM)
Smiles
[H][C@]12C[C@@H] (C) [C@]3 ([H]) CCC (=O) [C@@]3 (C) [C@@H] (OC (C) =O) [C@]1 ([H]) C (=C) C (=O) O2
Molecular Formula
C17H22O5
Molecular Weight
306.35
Storage Conditions
-20°C
Notes
For research use only.
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