Adenosylcobalamin
Adenosylcobalamin (AdoCbl) is the biologically active coenzyme form of vitamin B12, essential for methylmalonyl-CoA mutase and other enzymes like eliminases and aminomutases. It is used in research on inborn errors of metabolism, mitochondrial function, and as a critical cofactor in both in vitro enzymatic assays and in vivo metabolic studies.
Product Specifications
CAS Number
13870-90-1
Product Name Alternative
Endogenous Metabolite, Coenzyme B 12, Coenzyme B12, Coenzyme B-12, Cobamamide, AdoCbl, Adenosylcobalamin, inhibit, Human Endogenous Metabolite, EndogenousMetabolite, Inhibitor
Field of Research
Metabolism Research
Purity
95.29% (May vary between batches)
Solubility
H2O:4 mg/mL (2.53 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (1.27 mM) ; DMSO:41 mg/mL (25.96 mM)
Smiles
Nc1ncnc2n (cnc12) [C@H]1O[C@H] (C[Co++]) [C@H] (O) [C@@H]1O.[H][C@]12[N-]\C (=C (C) /C3=N/C (=C\C4=N\C (=C (C) /C5=N[C@]1 (C) [C@@] (C) (CC (N) =O) [C@@H]5CCC (N) =O) \[C@@] (C) (CC (N) =O) [C@@H]4CCC (N) =O) /C (C) (C) [C@@H]3CCC (N) =O) [C@] (C) (CCC (=O) NC[C@@H] (C) OP ([O-]) (=O) O[C@@H]1[C@@H] (CO) O[C@@H] ([C@@H]1O) n1cnc3cc (C) c (C) cc13) [C@H]2CC (N) =O
Molecular Formula
C72H100CoN18O17P
Molecular Weight
1579.58
Storage Conditions
-20°C
Notes
For research use only.
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