CU-T12-9
CU-T12-9 is a potent and selective TLR1/2 heterodimer agonist (EC50 = 52.9 nM) that activates the NF-κB pathway, inducing proinflammatory cytokines. This activity makes it a valuable research tool for studying innate/adaptive immunity in models of infection, vaccination, and inflammatory diseases.
Product Specifications
CAS Number
1821387-73-8
Product Name Alternative
Inhibit, infectious, inflammatory, influenza, pancreatic, obesity, Inhibitor, breast, diseases, CU T12 9, CUT129, CU-T-12-9, CU-T12-9, asthma, bladder, carcinoma, cancer, TLR, TLR1, TLR2, TLR1/2, Toll-like Receptor (TLR), specific
Field of Research
Immunology & Inflammation
Purity
99.84% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (13.8 mM) ; DMSO:250 mg/mL (690.02 mM)
Smiles
CNc1ccc (cc1-n1cnc (c1) -c1ccc (cc1) C (F) (F) F) [N+] ([O-]) =O
Molecular Formula
C17H13F3N4O2
Molecular Weight
362.31
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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