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DBPR108

DBPR108 is an orally active, dipeptide-based DPP4 inhibitor with an IC50 of 15 nM, demonstrating high selectivity as it does not inhibit DPP8 or DPP9. This compound is a valuable research tool for investigating DPP4 function in metabolic diseases, including diabetes, in both in vitro enzymatic assays and in vivo pharmacological studies.

Product Specifications

CAS Number

1186426-66-3

Product Name Alternative

Dipeptidyl Peptidase, DPP-4, DPP4, DPP, inhibit, Inhibitor, DBPR108, DBPR-108, DBPR 108

Field of Research

Protein Biochemistry

Purity

99.65% (May vary between batches)

Solubility

DMSO:≥ 25 mg/mL (77.07 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.17 mM)

Smiles

CC (C) (CC (=O) N1CCCC1) NCC (=O) N1C[C@@H] (F) C[C@H]1C#N

Molecular Formula

C16H25FN4O2

Molecular Weight

324.39

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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