DNA2 inhibitor C5
DNA2 inhibitor C5 is a specific, competitive small-molecule inhibitor of DNA2 nuclease activity (IC50: 20 μM) that also blocks its ATPase, helicase, and DNA-binding functions. This compound serves as a research tool to study DNA replication stress and is used in vitro to sensitize cancer cells to chemotherapeutic agents.
Product Specifications
CAS Number
35973-25-2
Product Name Alternative
DNA2 inhibitor C5, DNA-2 inhibitor C5, DNA2 nuclease, inhibit, Inhibitor
Field of Research
Cell Biology, Epigenetics & Chromatin; Pharmacology & Drug Discovery, Molecular Biology
Purity
98.00% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (8.54 mM) ; DMSO:31.25 mg/mL (133.46 mM)
Smiles
OC (=O) c1cnc2c (cccc2c1O) [N+] ([O-]) =O
Molecular Formula
C10H6N2O5
Molecular Weight
234.16
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog