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DNA2 inhibitor C5

DNA2 inhibitor C5 is a specific, competitive small-molecule inhibitor of DNA2 nuclease activity (IC50: 20 μM) that also blocks its ATPase, helicase, and DNA-binding functions. This compound serves as a research tool to study DNA replication stress and is used in vitro to sensitize cancer cells to chemotherapeutic agents.

Product Specifications

CAS Number

35973-25-2

Product Name Alternative

DNA2 inhibitor C5, DNA-2 inhibitor C5, DNA2 nuclease, inhibit, Inhibitor

Field of Research

Cell Biology, Epigenetics & Chromatin; Pharmacology & Drug Discovery, Molecular Biology

Purity

98.00% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (8.54 mM) ; DMSO:31.25 mg/mL (133.46 mM)

Smiles

OC (=O) c1cnc2c (cccc2c1O) [N+] ([O-]) =O

Molecular Formula

C10H6N2O5

Molecular Weight

234.16

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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