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Ertugliflozin L-pyroglutamic acid

Ertugliflozin L-pyroglutamic acid (PF-04971729) is a potent and selective oral inhibitor of the human sodium-glucose cotransporter 2 (hSGLT2), exhibiting an IC50 of 0.877 nM. It is a research compound used in both in vitro and in vivo studies for investigating potential treatments for type 2 diabetes mellitus.

Product Specifications

CAS Number

1210344-83-4

Product Name Alternative

Inhibitor, h-SGLT2, hSGLT2, Ertugliflozin L pyroglutamic acid, Ertugliflozin Lpyroglutamic acid, Ertugliflozin L-pyroglutamic acid, inhibit, SGLT, PF-04971729 L-pyroglutamic acid, Sodium-dependent glucose cotransporters

Field of Research

Pharmacology & Drug Discovery

Purity

98.71% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (7.07 mM) ; DMSO:125 mg/mL (220.85 mM)

Smiles

OC (=O) [C@@H]1CCC (=O) N1.CCOc1ccc (Cc2cc (ccc2Cl) [C@]23OC[C@] (CO) (O2) [C@@H] (O) [C@H] (O) [C@H]3O) cc1

Molecular Formula

C27H32ClNO10

Molecular Weight

566

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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