Gardiquimod
Gardiquimod is a selective TLR7 agonist and imidazoquinoline analog that suppresses HIV-1 infection in macrophages and activated PBMCs at concentrations below 10 μM. This small molecule is utilized in immunology and virology research to study innate immune activation and antiviral mechanisms in both cellular and animal models.
Product Specifications
CAS Number
1020412-43-4
Product Name Alternative
Cells, carcinoma, blood, Inhibitor, Gardiquimod, HepG2, HIV, HIV Protease, HIV-1, HIVProtease, mononuclear, Human immunodeficiency virus, PBMCs, macrophages, inhibit, liver, Toll-like Receptor (TLR), TLR7, TLR8, peripheral
Field of Research
Immunology & Inflammation, Infectious Disease & Virology, Protein Biochemistry
Purity
98.00% (May vary between batches)
Solubility
DMF:18 mg/mL (57.43 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:2 mg/mL (6.38 mM) ; DMSO:45 mg/mL (143.59 mM)
Smiles
CCNCc1nc2c (N) nc3ccccc3c2n1CC (C) (C) O
Molecular Formula
C17H23N5O
Molecular Weight
313.4
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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