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Gardiquimod

Gardiquimod is a selective TLR7 agonist and imidazoquinoline analog that suppresses HIV-1 infection in macrophages and activated PBMCs at concentrations below 10 μM. This small molecule is utilized in immunology and virology research to study innate immune activation and antiviral mechanisms in both cellular and animal models.

Product Specifications

CAS Number

1020412-43-4

Product Name Alternative

Cells, carcinoma, blood, Inhibitor, Gardiquimod, HepG2, HIV, HIV Protease, HIV-1, HIVProtease, mononuclear, Human immunodeficiency virus, PBMCs, macrophages, inhibit, liver, Toll-like Receptor (TLR), TLR7, TLR8, peripheral

Field of Research

Immunology & Inflammation, Infectious Disease & Virology, Protein Biochemistry

Purity

98.00% (May vary between batches)

Solubility

DMF:18 mg/mL (57.43 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:2 mg/mL (6.38 mM) ; DMSO:45 mg/mL (143.59 mM)

Smiles

CCNCc1nc2c (N) nc3ccccc3c2n1CC (C) (C) O

Molecular Formula

C17H23N5O

Molecular Weight

313.4

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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