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GSK-7975A

GSK-7975A is a cell-permeable, selective CRAC channel blocker suitable for oral administration in research. It is widely used in vitro and in vivo to investigate calcium signaling in immune cells, with applications in studying T-cell activation and related inflammatory pathways.

Product Specifications

CAS Number

1253186-56-9

Product Name Alternative

CRAC channel, CalciumChannel, Ca2+ channels, Calcium Channel, Ca channels, Inhibitor, GSK7975A, GSK-7975A, GSK 7975A, inhibit

Field of Research

Metabolism Research, Pharmacology & Drug Discovery

Purity

98.92% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (8.31 mM) ; DMSO:80 mg/mL (201.36 mM)

Smiles

Oc1ccc (Cn2ccc (NC (=O) c3c (F) cccc3F) n2) c (c1) C (F) (F) F

Molecular Formula

C18H12F5N3O2

Molecular Weight

397.3

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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