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BRD4 Inhibitor-10

BRD4 Inhibitor-10 is a potent and selective small molecule targeting the first bromodomain (BD1) of BRD4 with an IC50 of 8 nM. This compound is a valuable chemical probe for epigenetic research, utilized in vitro to study transcriptional regulation in oncology and inflammation, and has been employed in vivo in preclinical cancer models.

Product Specifications

CAS Number

1660117-38-3

Product Name Alternative

BRD4-BD1, BRD4 Inhibitor 10, BRD4 Inhibitor10, BRD-4 Inhibitor-10, BRD4 Inhibitor-10, inhibit, Inhibitor, EpigeneticReaderDomain, Epigenetic Reader Domain

Field of Research

Epigenetics & Chromatin, Epigenetics & Chromatin; Pharmacology & Drug Discovery

Purity

98.98% (May vary between batches)

Solubility

DMSO:125 mg/mL (291.03 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.31 mM)

Smiles

C[C@@H] (c1ccccc1) n1c (nc2cnc (cc12) C1CCOCC1) -c1cc (C) c (=O) n (C) n1

Molecular Formula

C25H27N5O2

Molecular Weight

429.51

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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