CCR2-RA-[R]
CCR2-RA-[R] is a potent allosteric antagonist of the C-C chemokine receptor type 2 (CCR2), exhibiting an IC50 of 103 nM. This small molecule inhibitor is a valuable research tool for studying CCR2-mediated pathways in vitro and for exploring its role in inflammatory and autoimmune disease models in vivo.
Product Specifications
CAS Number
512177-83-2
Product Name Alternative
CC chemokine receptor, CCR2 RA [R], CCR2RA[R], CCR-2-RA-[R], CCR2-RA-[R], CCR, CCR2, inhibit, Inhibitor
Field of Research
Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery
Purity
99.65% (May vary between batches)
Solubility
DMSO:125 mg/mL (355.32 mM) ; H2O:< 0.1 mg/mL (insoluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (9.38 mM)
Smiles
CC (=O) C1=C (O) C (=O) N ([C@@H]1C1CCCCC1) c1ccc (Cl) cc1F
Molecular Formula
C18H19ClFNO3
Molecular Weight
351.8
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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