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Dapagliflozin

Dapagliflozin (BMS-512148) is a selective SGLT2 inhibitor used in type 2 diabetes research. By competitively blocking renal glucose reabsorption, it promotes glucosuria and lowers blood glucose. This mechanism is studied in vitro and in vivo for metabolic disease and cardiovascular research applications.

Product Specifications

CAS Number

461432-26-8

Product Name Alternative

Sodium-dependent glucose cotransporters, SGLT, hSGLT2, Inhibitor, HIF1, inhibit, Dapagliflozin, BMS512148, BMS-512148, BMS 512148

Field of Research

Cardiovascular Research, Epigenetics & Chromatin, Pharmacology & Drug Discovery

Purity

99.50% (May vary between batches)

Solubility

H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4.5 mg/mL (11.01 mM) ; Ethanol:14 mg/mL (34.24 mM) ; DMSO:247.5 mg/mL (605.33 mM)

Smiles

O[C@H]1[C@@H] (O[C@H] (CO) [C@@H] (O) [C@@H]1O) C2=CC (CC3=CC=C (OCC) C=C3) =C (Cl) C=C2

Molecular Formula

C21H25ClO6

Molecular Weight

408.87

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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