Bortezomib
Bortezomib is a potent, selective, and reversible inhibitor of the 20S proteasome (Ki=0.6 nM) . Its antitumor activity is linked to NF-κB inhibition, leading to cell cycle arrest and apoptosis, making it a key tool for cancer research in both cellular and animal models.
Product Specifications
CAS Number
179324-69-7
Product Name Alternative
MG-341; PS-341; MLN341
Field of Research
Cardiovascular Research, Protein Biochemistry
Purity
>98%
Bioactivity
Proteasome inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 35 mg/ml) .
Smiles
CC (C) C[C@H] (NC (=O) [C@H] (Cc1ccccc1) NC (=O) c1cnccn1) B (O) O
Molecular Formula
C19H25BN4O4
Molecular Weight
384.2
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
N- (2-Pyrazine) carbonyl-L-phenylalanine-L-leucine boronic acid
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