BMS-794833
BMS-794833 is an ATP-competitive small molecule inhibitor targeting Met and VEGFR2 kinases. It serves as a prodrug for the active metabolite BMS-817378. This compound is utilized in cancer research for investigating angiogenesis and tumor growth in both cellular and animal models.
Product Specifications
CAS Number
1174046-72-0
Product Name Alternative
Vascular endothelial growth factor receptor, VEGFR, VEGFR2, inhibit, Met, Inhibitor, HGFR, BMS 794833, BMS794833, BMS-794833, c-Met, cMet, c-Met/HGFR, cMet/HGFR
Field of Research
Cardiovascular Research, Signal Transduction
Purity
98.00% (May vary between batches)
Solubility
DMSO:117.5 mg/mL (250.62 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.04 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
Nc1nccc (Oc2ccc (NC (=O) c3c[nH]cc (-c4ccc (F) cc4) c3=O) cc2F) c1Cl
Molecular Formula
C23H15ClF2N4O3
Molecular Weight
468.84
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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