4EGI-1
4EGI-1 is a small molecule inhibitor that competitively disrupts the eIF4E/eIF4G interaction with a binding affinity (K_D) of 25 μM. It serves as a valuable research tool for studying cap-dependent translation initiation in cancer biology and has been utilized in both cellular and in vitro assays to investigate oncogenic protein synthesis.
Product Specifications
CAS Number
315706-13-9
Product Name Alternative
4EGI 1, 4EGI1, 4EGI-1, Autophagy, Apoptosis, inhibit, Inhibitor, eIF-4E/eIF-4G, Eukaryotic Initiation Factor (eIF)
Field of Research
Cell Biology
Purity
96.80% (May vary between batches)
Solubility
DMSO:100 mg/mL (221.59 mM)
Smiles
OC (=O) C (\Cc1ccccc1[N+] ([O-]) =O) =N\Nc1nc (cs1) -c1ccc (Cl) c (Cl) c1
Molecular Formula
C18H12Cl2N4O4S
Molecular Weight
451.28
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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