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Pifithrin α

Pifithrin-α hydrobromide is a selective inhibitor of the tumor suppressor p53, blocking its transcriptional activity. It is widely used in research to study p53-mediated apoptosis and cellular stress responses, and has been applied in both in vitro and in vivo models to investigate ischemia, neurodegeneration, and chemotherapy-induced toxicity.

Product Specifications

CAS Number

63208-82-2

Product Name Alternative

PFT-α

Field of Research

Cell Biology, Neuroscience, Stem Cell & Developmental Biology

Purity

>98%

Bioactivity

P53 inhibitor

Form

Powder

Solubility

Soluble in DMSO (up to 25 mg/ml) .

Smiles

Br.Cc1ccc (cc1) C (=O) Cn1c2CCCCc2sc1=N

Molecular Formula

C16 H18 N2 O S · H Br

Molecular Weight

367.31

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

1- (4-Methylphenyl) -2- (4,5,6,7-tetrahydro-2-imino-3 (2H) -benzothiazolyl) ethanone · HBr

Available Sizes

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