Pifithrin α
Pifithrin-α hydrobromide is a selective inhibitor of the tumor suppressor p53, blocking its transcriptional activity. It is widely used in research to study p53-mediated apoptosis and cellular stress responses, and has been applied in both in vitro and in vivo models to investigate ischemia, neurodegeneration, and chemotherapy-induced toxicity.
Product Specifications
CAS Number
63208-82-2
Product Name Alternative
PFT-α
Field of Research
Cell Biology, Neuroscience, Stem Cell & Developmental Biology
Purity
>98%
Bioactivity
P53 inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 25 mg/ml) .
Smiles
Br.Cc1ccc (cc1) C (=O) Cn1c2CCCCc2sc1=N
Molecular Formula
C16 H18 N2 O S · H Br
Molecular Weight
367.31
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
1- (4-Methylphenyl) -2- (4,5,6,7-tetrahydro-2-imino-3 (2H) -benzothiazolyl) ethanone · HBr
Available Sizes
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