ML349
ML349 is a potent and selective inhibitor of acyl protein thioesterase 2 (APT2/LYPLA2), exhibiting an IC50 of 144 nM and a Ki of 120 nM. This small molecule is a valuable chemical probe for investigating protein S-depalmitoylation in cellular signaling pathways and related disease models in biochemical and cell-based studies.
Product Specifications
CAS Number
890819-86-0
Product Name Alternative
Phospholipase, LYPLA2, ML349, ML-349, ML 349, Inhibitor, inhibit, APT-2
Field of Research
Metabolism Research
Purity
99.59% (May vary between batches)
Solubility
DMSO:12.5 mg/mL (27.5 mM)
Smiles
COc1ccc (cc1) N1CCN (CC1) C (=O) c1cc2CS (=O) (=O) c3ccccc3-c2s1
Molecular Formula
C23H22N2O4S2
Molecular Weight
454.56
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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